Patient Resources

31 Gennaio 2025
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Patient Resources

My consent is required to process sensitive personal data under certain privacy laws, and I have the right to withdraw my consent by visiting “Your Privacy Choices” on AbbVie’s website. SYNTHROID is contraindicated in patients with uncorrected adrenal insufficiency see Warnings and Precautions (5.4). Administer SYNTHROID at least 4 hours before or after drugs known to interfere with SYNTHROID absorption see Drug Interactions (7.1). A portion of the conjugated hormone reaches the colon unchanged and is eliminated in the feces.

Protein-bound thyroid hormones exist in reverse equilibrium with small amounts of free hormone. Many drugs and physiologic conditions affect the binding of thyroid hormones to serum proteins see Drug Interactions (7). Thyroid hormones do not readily cross the placental barrier see Use in Specific Populations (8.1). Many drugs and physiologic conditions affect the binding of thyroid hormones to serum proteins see DRUG INTERACTIONS. Thyroid hormones do not readily cross the placental barrier see Use In Specific Populations. Myxedema coma is a life-threatening emergency characterized by poor circulation and hypometabolism and may result in unpredictable absorption of levothyroxine sodium from the gastrointestinal tract.

Acute Adrenal Crisis In Patients With Concomitant Adrenal Insufficiency

Synthroid is also used in patients who need surgery and radioiodine therapy to manage a type of thyroid cancer called well-differentiated thyroid cancer. The hypothalamus and pituitary react to these low levels of thyroid hormone by producing more TRH and TSH. Biotin supplementation is known to interfere with thyroid hormone immunoassays that are based on a biotin and streptavidin interaction, which may result in erroneous thyroid hormone test results. Stop biotin and biotin-containing synthroid seaweed supplements for at least 2 days prior to thyroid testing. The SYNTHROID dosage is based on the target level of TSH suppression for the stage and clinical status of thyroid cancer. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown.

Hypothyroidism:

Consider the potential for food or drug interactions and adjust the administration or dosage of SYNTHROID as needed see Dosage and Administration (2.1), Drug Interactions (7.1), and Clinical Pharmacology (12.3). The signs and symptoms of overdosage are those of hyperthyroidism see WARNINGS AND PRECAUTIONS and Adverse Reactions. Seizures occurred in a 3-yearold child ingesting 3.6 mg of levothyroxine. Titrate the dose of SYNTHROID carefully and monitor response to titration to avoid these effects see DOSAGE AND ADMINISTRATION. Consider the potential for food or drug interactions and adjust the administration or dosage of SYNTHROID as needed see DOSAGE AND ADMINISTRATION, DRUG INTERACTIONS and CLINICAL PHARMACOLOGY.

Check with your physician for additional information about side effects. Notify your doctor if you experience serious side effects of Synthroid including rapid heartbeat, fluttering in your chest, or chest pain. Get medical help right away, if you have any of the symptoms listed above. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Enter medications to view a detailed interaction report using our Drug Interaction Checker. Do not share this medicine with another person, even if they have the same symptoms you have.

  • Oral levothyroxine sodium is a synthetic T4 hormone that exerts the same physiologic effect as endogenous T4, thereby maintaining normal T4 levels when a deficiency is present.
  • Assess compliance, dose of medication administered, and method of administration prior to increasing the dose of SYNTHROID see Warnings and Precautions (5.1) and Use in Specific Populations (8.4).
  • Thyroid hormone increases metabolic clearance of glucocorticoids.
  • Serum TSH levels should be monitored and the SYNTHROID dosage adjusted during pregnancy.

Levoxyl treats hypothyroidism (low thyroid hormone) and treats or prevents goiter. SYNTHROID is not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients, as there are no clinical benefits and overtreatment with SYNTHROID may induce hyperthyroidism. By visiting Synthroid.com, patients can access additional support and resources to understand and manage their hypothyroidism. The Before Breakfast Club is a program designed to help support your patients on SYNTHROID therapy. After joining, patients will receive exclusive benefits including savings, tips, and tools to help your patients make the most of their SYNTHROID treatment.

  • This is important because the amount of medicine you need is very precise.
  • Thyroid hormones may increase the risk of coronary insufficiency when sympathomimetic agents are administered to patients with coronary artery disease.
  • Approximately 80% of the daily dose of T4 is deiodinated to yield equal amounts of T3 and reverse T3 (rT3).
  • Follow your doctor’s dosing instructions and try to take the medicine at the same time each day.

What happens if I miss a dose?

SYNTHROID is contraindicated in patients with uncorrected adrenal insufficiency see WARNINGS AND PRECAUTIONS. Long-term carcinogenicity studies in animals to evaluate the carcinogenic potential of levothyroxine have not been performed. Studies to evaluate mutagenic potential and animal fertility have not been performed.

RxList does not provide medical advice, diagnosis or treatment. Administer SYNTHROID as a single daily dose, on an empty stomach, one-half to one hour before breakfast. Pregnant and lactating females need to discuss the dose and use of this medication with their caregivers. This document does not contain all possible side effects and others may occur.

Tell your doctor if you have an untreated or uncontrolled adrenal gland disorder, a thyroid disorder called thyrotoxicosis, or if you have any recent or current symptoms of a heart attack. Biochemical assessment incorporated measurement of serum TSH, T3, and T4. TSH lower limit of quantification was 0.2 mIU/L and upper limit of normal was 5.6 mIU/L, as indicated by the shaded area. SYNTHROID is not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis. With the Synthroid Delivers Program, everyone with a Synthroid prescription pays the same price, every time, with no hidden out-of-pocket costs or price fluctuations.

A TSH test is used to check the level of thyroid-stimulating hormone in the blood. Your TSH level can indicate if your thyroid gland is working properly. With hypothyroidism, the thyroid is unable to produce enough thyroid hormone. Thyroid hormone levels in the body provide signals to the hypothalamus and pituitary, so they know whether to release more or less TRH and TSH.